Last edited by Zulkilmaran
Saturday, August 1, 2020 | History

4 edition of The role of oligodendroglial cells in the CNS radiation response found in the catalog.

The role of oligodendroglial cells in the CNS radiation response

Shelley Lynn Atkinson

The role of oligodendroglial cells in the CNS radiation response

by Shelley Lynn Atkinson

  • 284 Want to read
  • 18 Currently reading

Published by National Library of Canada in Ottawa .
Written in English


Edition Notes

Thesis (M.Sc.) -- University of Toronto, 2003.

SeriesCanadian theses = -- Thèses canadiennes
The Physical Object
FormatMicroform
Pagination2 microfiches : negative.
ID Numbers
Open LibraryOL20125764M
ISBN 100612782115
OCLC/WorldCa56329516

Define oligodendroglial. oligodendroglial synonyms, oligodendroglial pronunciation, oligodendroglial translation, English dictionary definition of oligodendroglial. n. Neuroglia consisting of oligodendrocytes. pl n a class of cells in the central nervous system which produce myelin Noun 1. oligodendroglia - tissue. Gliomas have been treated by a specialized team including neurosurgery, radiation therapy, and neuro-oncology, as well as depending on integrated sophisticated facilities and multi-professional team. Despite these huge efforts to glioma treatment, glioblastoma, one of the most frequent gliomas, has median life expectance for just 15 months, so these results are still an unmet need. Related to Author: Johnny Camargo.

5-years; PMID — "Prospective randomized trial of low- versus high-dose radiation therapy in adults with supratentorial low-grade glioma: initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group study." (Shaw E et al. J Clin Oncol. May 1;20(9)). May 01,  · Penfield went to Spain in the spring of to work with Río-Hortega and Cajal, which resulted in a fruitful 5 months of study. During this trip, he published several articles, including a landmark report in which he completed the characterization of the “third element” of Cajal (non-astrocyte glial cells) and its relationship to classical scrapbookingnadiastpierre.com by:

An adult central nervous system tumor is a disease in which abnormal cells form in the tissues of the brain and/or spinal cord. There are many types of brain and spinal cord scrapbookingnadiastpierre.com tumors are formed by the abnormal growth of cells and may begin in different parts of the brain or spinal cord. Together, the brain and spinal cord make up the central nervous system (CNS). Sep 30,  · These observations highlight the critical role that the blood-brain barrier plays in preventing antineoplastic therapies from reaching the central nervous system in therapeutic concentrations. It also summarizes data from a variety of approaches designed to improve drug delivery to the central nervous scrapbookingnadiastpierre.com by: 2.


Share this book
You might also like
Wisdom for the wise

Wisdom for the wise

Price list and specimens of inks.

Price list and specimens of inks.

Literature for children

Literature for children

The Air Force, conscription, and the all-volunteer force

The Air Force, conscription, and the all-volunteer force

Der Deutsche Protestantismus Und Die Soziale Frage, 1870-1919

Der Deutsche Protestantismus Und Die Soziale Frage, 1870-1919

The eMarketplace

The eMarketplace

Castle War!

Castle War!

Schools without scholars

Schools without scholars

Chronicles of Chaldaean kings (626-556 B.C.) in the British Museum

Chronicles of Chaldaean kings (626-556 B.C.) in the British Museum

Comprehensive survey of: Elk River sub-basin

Comprehensive survey of: Elk River sub-basin

Mio, my son.

Mio, my son.

Eroticism in Western art

Eroticism in Western art

The role of oligodendroglial cells in the CNS radiation response by Shelley Lynn Atkinson Download PDF EPUB FB2

Oligodendrocyte formation in the adult brain is associated with glial-restricted progenitor cells, known as oligodendrocyte progenitor cells (OPCs). SVZ cells migrate away from germinal zones to populate both developing white and gray matter, where they differentiate Location: Central nervous system.

Research Highlights The oligodendrocyte is the CNS cell type responsible for production of the myelin sheath. Newly differentiated oligodendrocyte progenitor cells mediate myelin repair (remyelination). Transplantation of exogenous progenitors or targeting endogenous ones may enhance scrapbookingnadiastpierre.com by: Radiation-induced damage in the central nervous system: an interpretation of target cell responses.

Patterson RC. Observations on the interactions of Schwann cells and astrocytes following X-irradiation of neonatal rat spinal cord. J Neurocytol. Bliven SF, Howard J. Response of rat spinal cord to single and fractionated doses of Cited by: Glial Cells: Structure and Function in Health and Disease.

STUDY. PLAY. Glial Cells-non-neuronal support cells in the CNS-provide physical protection and maintain homeostatic for neurons of brain and spinal cord times as many glial cells as there are neurons in CNS.

-unknown role -thought that they may interact with cerebral endothelium. NG2 cells are a subtype of widely distributed glial cells representing around 5 % of the total number of cells in the mammalian central nervous system (CNS). NG2 cells are mostly known for their.

Cellular senescence is a normal biological process that is initiated in response to a range of intrinsic and extrinsic factors that functions to remove irreparable damage and therefore potentially harmful cells, from the proliferative pool.

Senescence can therefore be thought of in beneficial terms as a tumour scrapbookingnadiastpierre.com by: Nonetheless, there is a role for medical or radiation-based management of these tumors in the setting of residual or recurrent disease. The role of chemotherapy is changing, especially in the adult population, where genomic data have revealed distinct mutations present in the majority of oligodendrogliomas that correlate with prognosis.

Feb 01,  · In the human demyelinating disorder multiple sclerosis, and its animal model experimental allergic encephalomyelitis, there is a breakdown of the blood-brain barrier and an infiltration of immune cells into the CNS. Infiltrating T lymphocytes and macrophages are believed to be key mediators of the disease process.

Considerable circumstantial and experimental evidence has suggested that the Cited by: Aug 11,  · Cellular senescence is a normal biological process that is initiated in response to a range of intrinsic and extrinsic factors that functions to remove irreparable damage and therefore potentially harmful cells, from the proliferative pool.

Senescence can therefore be thought of in beneficial terms as a tumour suppressor. In contrast to this, there is a growing body of evidence suggesting that Cited by: Apr 29,  · Resveratrol is a natural polyphenol compound highly found in red wine that displays several beneficial effects on the central nervous system Glioprotective Effect of Resveratrol: an Emerging Therapeutic Role for Oligodendroglial Cells In summary, this is the first study showing the glioprotective effect of resveratrol on Cited by: 7.

Nov 07,  · Treatment-induced CNS toxicity remains a major cause of morbidity in patients with cancer.

Advances in the design of safe radiation procedures have been counterbalanced by widespread use of combined radiotherapy and chemotherapy, development of radiosurgery, and the increasing number of long-term survivors. Although classic radionecrosis and chemonecrosis have become less Cited by: Oligodendroglia.

Myelin sheath. Myelin. The dark ring consists of layers of oligodendroglial cell membrane wrapped around the axon. In the CNS, myelin is made by oligodendroglial cells; in peripheral nerves by Schwann cells.

Each Schwann cell makes one segment of myelin; each oligodendrocyte makes multiple segments of myelin that wrap. Genetic abnormalities in oligodendroglial and ependymal tumours Article · Literature Review in Journal of Neurology (12) · January with 8 Reads How we measure 'reads'.

Find out information about Oligodendroglial cells. Glial cell responsible for elaborating myelin in the central nervous system Explanation of Oligodendroglial cells.

Simons, "Control of oligodendroglial cell number by the miR cluster," Development, vol. (57) It is unclear, though, whether this histologic appearance is truly reflective of a derivation from oligodendroglial cells.

Alternatively, these cells may be derived from more primitive tumor stem cells that can differentiate along a line of oligodendroglial differentiation.

@article{osti_, title = {Cell fate control in the developing central nervous system}, author = {Guérout, Nicolas and Li, Xiaofei and Barnabé-Heider, Fanie, E-mail: [email protected]com}, abstractNote = {The principal neural cell types forming the mature central nervous system (CNS) are now understood to be diverse.

This cellular subtype diversity originates to a large extent. Oligodendroglial cells synonyms, Oligodendroglial cells pronunciation, Oligodendroglial cells translation, English dictionary definition of Oligodendroglial cells.

Any of the neuroglial cells of the central nervous system that are responsible for the formation of myelin sheaths in the white matter and that, in the. Oligodendroglia. STUDY. Flashcards. Learn. Write. Spell. Test.

PLAY. Match. Gravity. Created by. juanjaramillo. Terms in this set (4) A year-old woman is diagnosed with multiple sclerosis. Name the central nervous system cells that are destroyed in this disease.

Oligodendrocytes (these cells are attacked in an autoimmune process resulting in. The central nervous system normally lacks lymphoid aggregates.

The cellular and molecular events leading to neoplastic lymphocytic infiltration of the central nervous system are seen in PCNSLs. Primary lymphoma of the central nervous system (CNS) is defined as diffuse large B cell lymphoma confined to the central nervous scrapbookingnadiastpierre.com: Meral Kurt, Candan Demiröz Abakay, Ali Altay.

oligodendroglia cell: n. A form of oligodendrocyte that is a component of central nervous system tissue and that may contribute to formation of the myelin sheath around axons of neurons.

oligodendroglial tumors [11]. They showed that the mitogen PDGF, which has been shown to have a role in neoplastic proliferation and is highly expressed in human glial tumors, is also expressed in O and may be acting in an autocrine stimulatory loop.

Chan examined the expression of VEGF and its receptors in oligodendroglial tumors [12].Investigation of the underlying mechanisms of differential radiation response between normal astrocytes and glioma cells is thus significant for improvement of glioma treatment.

Here, we report on the differential radiation responses between normal astrocytes and glioma cells at the transcriptome scrapbookingnadiastpierre.com: Liang Gong, Jiacheng Gu, Jianwei Ge, Xiang Wu, Chao Zhang, Chun Yang, Weiji Weng, Guoyi Gao, Junfeng.The exact mechanisms by which radiation necrosis develops are likely due to complex interactions of endothelial cells, astrocytes and perhaps microglia and oligodendrocytes.

Radiation induced neurocognitive decline is likely due to radiation effects on neurons and astrocytes but other cells may have an undefined role.